Low Dose Naltrexone (LDN) – Understanding the Benefits

Low Dose Naltrexone (LDN) – Understanding the Benefits

July 29, 2025

How Westmoreland Pharmacy + Compounding Supports Patients with Personalized LDN Formulations

Low Dose Naltrexone (LDN) is gaining increased attention for its potential role in managing chronic pain, inflammation, and autoimmune-related conditions. At Westmoreland Pharmacy + Compounding, we work closely with patients and healthcare providers to compound customized LDN formulations that meet each individual’s needs, offering an alternative solution when conventional treatments fall short. 

Whether you’re a patient exploring new options or a provider seeking trusted compounding support, our pharmacy is here to help you navigate the possibilities of LDN therapy. 

What Is Low Dose Naltrexone?

Naltrexone is a medication traditionally used at higher doses (50 mg or more) to treat opioid and alcohol dependence. However, when compounded in much smaller doses, typically between 0.5 mg and 4.5 mg, it is believed to act on the immune system, endorphin production, and inflammation pathways, offering therapeutic potential beyond its original purpose. 

Because low dose naltrexone is not available commercially, it must be prepared by a licensed compounding pharmacy like Westmoreland Pharmacy + Compounding. Find out more

How LDN May Help: A Versatile Option for Chronic Conditions

Chronic Pain & Inflammation

LDN is frequently used as a non-opioid option for managing various types of pain and inflammatory conditions, especially when standard therapies may not be effective or not well tolerated.

Conditions where LDN may be helpful include:

  • Neuropathic pain (nerve-related pain)
  • Fibromyalgia
  • Rheumatoid arthritis
  • Crohn’s disease
  • Endometriosis
  • Migraines
  • Complex Regional Pain Syndrome (CRPS)

LDN is thought to modulate the immune response and reduce inflammation at the cellular level. It may also stimulate the release of endorphins, your body’s natural pain-relieving chemicals, offering meaningful symptom relief for those struggling with persistent discomfort.

LDN and Autoimmune Conditions

LDN for Fibromyalgia & Chronic Fatigue Syndrome (CFS/ME)

Many individuals with fibromyalgia or chronic fatigue syndrome have reported improvements in pain, sleep, cognitive clarity (“brain fog”), and energy levels with LDN therapy. 

  • Helps regulate neuroinflammation, often present in both conditions 
  • May improve the body’s pain tolerance and energy metabolism 
  • Offers a low-risk, well-tolerated alternative to conventional medications 

At Westmoreland Pharmacy + Compounding, we can tailor LDN capsules, creams, or liquids to suit each patient’s preferred dose and delivery method. 

LDN may offer support for individuals with autoimmune diseases, where the body’s immune system mistakenly attacks healthy tissues. LDN is believed to help rebalance immune activity and reduce inflammatory flares.

Autoimmune conditions where LDN is being explored:

Because LDN may help regulate immune function without the immune suppression seen in some pharmaceuticals, it is often considered a complementary therapy in functional or integrative care settings.

Why Is LDN Compounded?

LDN is only commercially available in limited dosage forms, which is why custom compounding is essential. This allows your provider to prescribe the exact strength and form that’s right for your treatment plan.

Benefits of Compounded Low Dose Naltrexone:

  • Customized Dosages: Starting as low as 0.1 mg and titrated based on tolerance and symptom response
  • Flexible Delivery Options: Capsules, flavored suspensions, or topical creams
  • Ingredient Sensitivity Support: Free from allergens, dyes, or fillers upon request
  • Combination Therapy Options: May include complementary ingredients like B vitamins or antioxidants

Is LDN Right for You?

LDN is being explored for use in a wide range of chronic and complex conditions, including: 

  • Irritable Bowel Syndrome (IBS) 
  • Post-Traumatic Stress Disorder (PTSD) 
  • Autoimmune skin conditions 
  • Menstrual pain and hormone imbalance 
  • Long COVID symptoms (emerging area of study) 

Your healthcare provider can help determine if LDN is appropriate based on your symptoms, medical history, and current medications. 

Important Note: Because LDN blocks opioid receptors, it should not be used alongside opioid medications (e.g., morphine, oxycodone, hydrocodone). 

Why Choose Westmoreland Pharmacy + Compounding for LDN?

As a trusted, PCAB-accredited compounding pharmacy, Westmoreland Pharmacy is committed to the highest standards of quality, safety, and personalized care. We compound low dose naltrexone according to a provider’s exact specifications, using pharmaceutical-grade ingredients and rigorous quality control protocols.

We provide:

  • Expert collaboration with prescribers
  • Quick turnaround and consistent refills
  • Friendly, knowledgeable support from our pharmacy team
  • Local service with nationwide shipping available

Ready to Learn More About LDN?

If you or your provider are considering Low Dose Naltrexone as part of a pain, autoimmune, or chronic condition treatment plan, our compounding team is here to help.

Learn more about our full range of compounded specialties and how LDN fits into our anti-aging and wellness therapies.